Tailored for membrane protein drug discovery, Distolife has established a multi-dimensional, systematic membrane protein functional evaluation platform to precisely characterize the physiological activity and pharmacological properties of membrane proteins. Our services encompass receptor functional validation, BRET functional analysis, and comprehensive activity evaluation, providing full-spectrum support for target functional mechanisms and drug candidate assessment.
Service Content:
(1) Receptor Functional Validation
For signaling receptors such as GPCRs:
- Ligand binding assessment
- Signaling pathway detection
- Receptor activation assessment
(2) BRET Functional Analysis Platform
Establishment of BRET-based systems for detecting membrane protein interactions and signaling:
- GPCR activation detection
- Protein-protein interaction analysis
- Signal transduction research
(3) Membrane Protein Activity Assessment
- Ligand binding assays
- Stability analysis
- Biochemical function validation
- Biophysical property assessment
Service and Duration (varies by assay system):
| Service Details | Lead Time |
| Individual function testing | 2–4 Weeks |
| Establishment of a functional system | 6–10 Weeks |
| Comprehensive evaluation items | 8–12 weeks |
Service Delivery Standards:
- Experimental design plan;
- Raw test data;
- Data analysis results;
- Curve-fitting results;
- Parameters such as EC50/IC50 (if applicable);
- Functional evaluation report.
- Cell samples;
Leave a Message
Inquiry Submitted
Thank you for your inquiry. Our team will get back to you as soon as possible.